Prevalence and Characteristics of Immunomediated Neuropathies in a Group of Patients With Autoimmune Diseases.

OBJECTIVE: To determine the prevalence and the clinical-neurophysi ological characteristics of immunomediated peripheral neuropathies (PN) in a group of patients with systemic autoimmune diseases.

CONCLUSIONS: The first national prevalence rate of PNs in patients with systemic autoimmune diseases was provided: 30.5%. No comparative data were found in the international bibliography. Sensory-motor polyneuropathy was the most frequently observed form of PN, followed by mononeuritis multiplex. The NPs appeared with the same frequency both at the onset and during the course of the diseases under study; these predominated at the onset of vasculitis and primary Sjögren syndrome. The compromise of the peripheral nervous system is underdiagnosed.

The rest of this article is here.


Peripheral neuropathy is disorder of nerve(s) apart from the brain and spinal cord. Patients with peripheral neuropathy may have tingling, numbness, unusual sensations, weakness, or burning pain.

The peripheral nervous system or PNS, is part of the nervous system, and consists of the nerves and neurons that reside or extend outside the central nervous system to serve the limbs and organs.

My Analysis: From my web discussion group, many WG patients complain of tingling in the limbs (arms, hands, legs and feet). I also have problems with tingling in my arms and shoulders. I haven’t mentioned this sensation to my doctors (not thinking that it could be a problem).

Also, some of the treatments (i.e. advil and other types of ibuprofen medications) are not good for my kidneys. I am not sure how dangerous this condition can be for the patient.

If you have this problem, you should make sure that your doctor knows about it.


About Cyn Bagley

My life is a mixture of travel, jobs, and disease. You can find some of my novels on under the name Cyn Bagley.
This entry was posted in Wegener's Granulomatosis. Bookmark the permalink.

2 Responses to Prevalence and Characteristics of Immunomediated Neuropathies in a Group of Patients With Autoimmune Diseases.

  1. A dear person in my life who was just three days ago diagnosed with T-cell lymphoma also experienced these neuropathy symptoms along with severe vertigo requiring hospitalization back in February of last year (2007).Just to add…Thank you, Cyn…be well.

  2. Hi mapiprincesa,I am sorry to hear about your friend’s (family?) serious disease. It can be really stunning to the family. Hugs…Yours, Cyn

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