Tumor of the heart in a young woman; a rare manifestation of Wegener granulomatosis

Summary 

Wegener granulomatosis may rarely present with tumor masses that are in areas not typically involved by the disease. Although some cases have an associated positive anti-neutrophilic cytoplasmic antibodies, other cases do not, especially those of the limited form. To prevent misdiagnosis and ensure prompt treatment, it is extremely important to consider Wegener granulomatosis even in cases without the classic clinical findings. We report a case of a 19-year-old woman with no prior significant medical history who presented with persistent ventricular tachycardia and a papillary muscle mass in her left ventricle which upon excision and tissue evaluation demonstrated histologic changes of Wegener granulomatosis.

You can find the abstract here.

What I have to say: Wegener’s Granulomatosis (or GPA) can manifest itself in many different ways. This one is new for me. If you can’t get a good diagnosis or your diagnosis keeps changing to fit the symptoms, you might consider asking your doctor to check if you have WG (or at least get someone to do a differential diagnosis.) If you are C-ANCA or P-ANCA positive, then you are likely to have one of the Vasculitis diseases. If you aren’t, then it might mean that you need a differential diagnosis. Just because you are ANCA negative, does not mean you are safe.

We have several WG diagnosed patients who are not ANCA positive.

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About Cyn Bagley

My life is a mixture of travel, jobs, and disease. You can find some of my novels on amazon.com under the name Cyn Bagley.
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